In vitro, in vivo and in silico anti-hyperglycemic inhibition by sinigrin

Qamar ABBAS; Mubashir HASSAN; Hussain RAZA; Song-Ja KIM; Ki-Wha CHUNG; Gwang-Hoon KIM; Sung-Yum SEO

In vitro, in vivo and in silico anti-hyperglycemic inhibition by sinigrin

Qamar ABBAS; Mubashir HASSAN; Hussain RAZA; Song-Ja KIM; Ki-Wha CHUNG; Gwang-Hoon KIM; Sung-Yum SEO.

Asian Pacific Journal of Tropical Medicine ; (12): 372-379, 2017.

Article in Chinese | WPRIM | ID: wpr-972641

ABSTRACT

ABSTRACT

Objective To evaluate the anti-hyperglycemic potential of sinigrin using in vitro, in silico and in vivo streptozotocin (STZ) induced hyperglycemic zebrafish model. Methods The in vitro enzyme inhibition assay was carried out to determine the IC

Anti-hyperglycemia; MD simulations; Sinigrin; Zebrafish; α-amylase; α-glucosidase

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Asian Pacific Journal of Tropical Medicine Year: 2017 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Asian Pacific Journal of Tropical Medicine Year: 2017 Type: Article