Serum Neopterin Concentration in Children with Graves' Disease / 대한소아내분비학회지
Journal of Korean Society of Pediatric Endocrinology
;
: 68-72, 1998.
Article
in Korean
| WPRIM
| ID: wpr-97279
ABSTRACT
PURPOSE:
Neopterin is a marker of activation of the T-lymphocyte/monocyte axis. We measured serum neopterin concentration to investigate whether serum neopterin levels are increased in children with Graves' disease and whether serum neopterin measurement can be used as a marker of disease activity in Graves disease.METHODS:
Twenty children with Graves' disease(3 boys and 17 girls) and 15 healthy children(7 boys and 8 girls) are enrolled in this study. Serum neopterin concentrations are measured by radioimmunoassay.RESULTS:
Neopterin concentration in children with Graves' disease(1.59+/-1.25ng/ml) is not higher than that of healthy children(1.51+/-0.73ng/ml). Neopterin concentration is not influenced by thyroid function and remission state.CONCLUSION:
Serum neopterin level in children with Graves' disease can not be used as a marker of activity.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Axis, Cervical Vertebra
/
Thyroid Gland
/
Radioimmunoassay
/
Graves Disease
/
Neopterin
Limits:
Child
/
Humans
Language:
Korean
Journal:
Journal of Korean Society of Pediatric Endocrinology
Year:
1998
Type:
Article
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