Research progress of broadly neutralizing antibodies against human immunodeficiency virus / 中国生物制品学杂志
Chinese Journal of Biologicals
;
(12): 217-2023.
Article
in Chinese
| WPRIM
| ID: wpr-974737
ABSTRACT
@#Acquired immune deficiency syndrome(AIDS)is a global public health issue,which has a major impact on human life and health.As the main pathogen of AIDS,human immunodeficiency virus type 1(HIV-1)has high variability and latent characteristics,there are no available vaccines and drugs to prevent and cure AIDS.The broadly neutralizing antibodies(bNAbs)against HIV-1 can induce effective immune response to HIV-1 infection in vivo,and neutralize different types of strains at the same time,which have great application potential in preventing HIV-1 infection and controlling the process of AIDS.In this paper,the production and acquisition,classification and characteristics as well as application of HIV-1bNAbs are reviewed so as to provide a reference for the subsequent research on HIV-1 vaccine and development of antibody drugs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Biologicals
Year:
2023
Type:
Article
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