The homeostasis during cardiopulmonary bypass / Монголын Анагаах Ухаан

ABSTRACT

BackgroundOpen cardiac surgery in CPB condition has increased dramatically in the recent 5 years. Therefore,multidisciplinary researches are needed on this new technological method. The surgical results andperioperative complications depends on keeping normal level of homeostasis parameters during CPBin the open heart surgery.Materials and MethodsTo study the parameters of homeostasis during cardiopulmonary bypass, we concluded retrospectivesample survey using CPB reports from 535 patients, who underwent cardiac surgery with CPB between2008 and 2012, in 3rd Hospital’s cardiovascular surgery department.We calculated average parameters of homeostasis, and studied heart recovery process.ResultIn recent 5 years, artery blood indicators were pH=7.45±0.06, paCO2=28.8±5.86 mm.Hg,paO2=398.3±99.33 mm.Hg, BE=-4.15±2.51 mmol/l, HCO¯3=20.57±2.18 mmol/l, Ht=28.15±5%,K+=4.12±0.87 mmol/l and Na+=140±3.22 mmol/l during open cardiac surgery in CPB condition(n=535).80.3% of patients’ heart spontaneously recovered and stabilized with sinus rhythm. 16.4% of them wererecovered with fibrillation while 2.1% of them were recovered with adrenomimetic support and 1.2% ofthem were recovered with strong adrenomimetic support and defibrillation.Conclusions:1. When acid and alkaline balance was normal during CPB, hyperoxia and hypocapnia are appearedthrough gas analysis (p=0.0001).2. While blood cardioplegic solution is used, heart is refreshed with 80.3% sinusial rhythm(p=0.0001).