ANALYSIS OF OLEUM HIPPOPHAES / Монголын эм зүй, эм судлал

ABSTRACT

Introduction: Hippophaes L.s is dioecious branched shrub or small tree with 1.5-3 m. height (Elaeagnaceae). Medicinal raw materials are Fructus Hippophaes from which we can get the Oleum Hippophaes. Hippophaes is widely used in traditional medicine as well as in the official medicine. Hippophaes oil is unique medication and natural concentrated product of bioactive substances. It is used for treatment gastrointestinal tract’s and gynecological diseases, cancer and atherosclerosis. Also it stimulates reparative processes, inhibits the activity of gastric proteases, activates secretion and motor function of intestine, reduces the level of cholesterol and lipids, and it has antioxidant properties. Widespread use of Oleum Hippophaes has led to the increasing number of producers and simultaneous increasing of poor quality products.The purpose of this work was to identify authenticity of conformity Oleum Hippophaes and to make quantitative analysis of carotenoids according to the Temporary Pharmacopeial monograph. The object of our analysis was Oleum Hippophaes (production of CJSC “Altayvitamines”) [1].To achieve this goal we had to make the following tasks 1) to determine the refractive index and density of Oleum Hippophaes for qualitative analysis; 2) tomake quantitative analysis of carotenoids in Oleum Hippophaes by spectrophotometry. In the course of this work we made qualitative and quantitative analysis of Oleum Hippophaes. We have set quality parameters such as refractive index and density. The refractive index amounted n 20 = 1,472 (1,468 - 1,477), and density of Oleum Hippophaes was 0.919 g / ml (0.916 - 0.922 g / ml). According to the quantitative analysis the content of total carotenoids in Oleum Hippophaes was about 205 mg% (should be not less than 180 mg%) [2,3].Thus, the qualitative and quantitative analysis of Oleum Hippophaes revealed conformity with basic parameters of the Temporary Pharmacopoeial monograph ¹42- 1698-87.References1) Samylina I.A., Muraeva D.A., Yakovlev G.P. Pharmacognosy. – M Medicine, 2007. 400 p.2) Temporary pharmacopoeia article ¹42-1698-87.3) State Pharmacopoeia of the USSR. Ed 10 (part 2) Common methods of physico-chemical, chemical, and biological research. USSR Ministry of Health.- 10th ed., Ext. - M Medicine, 1968. - 743 p.