Protease and protease inhibitor in cancer management

ABSTRACT

Protease is responsible for many physiological functions and can act as growth factor for both malignant and normal cells in the processes of the cell division and DNA biosynthesis. There was clear relation between metastatic tumors and protease. The protease inhibitors found in the natural environment or synthesized but both have not been used in the treatment of human cancer. Currently, the protease inhibitors are studying thoroughly on their mechanism, action and application in the anti-cancer.