Analysis of Clinical Types and Retinal Nerve Fiber Layer According to Optic Disc Appearances

ABSTRACT

PURPOSE: To evaluate the clinical characteristic of retinal nerve fiber layer (RNFL) and The clinical types of glaucoma according to optic disc appearances. METHODS: Sixty eyes in 60 patients with glaucoma were evaluated retrospectively. Complete ophthalmologic examination, optical coherent tomography (OCT), automated perimetry, stereoscopic optic disc photography and RNFL photography were performed. We classified optic disc pattern into focal, myopic, generalized enlargement, senile sclerotic, and normal appearance types. RESULTS: In 60 eyes with glaucoma, 15 eyes were adult-onset primary open-angle glaucoma (Adult-onset POAG), 22 eyes were normal-tension glaucoma (NTG), 10 eyes were juvenile-onset open-angle glaucoma (JPOAG), and 13 eyes were secondary glaucoma. JPOAG patients were significantly more detected in association with myopic optic disc type (P<0.05). OCT- measured temporal RNFL thickness in focal optic disc pattern were significantly lower than that in myopic optic disc pattern (P<0.05). Age was significantly correlated with temporal RNFL thickness in our study subjects (P<0.036, r=-0.272). CONCLUSIONS: Our study revealed that JPOAG patients may have a relationship with myopic optic disc type. OCT-measured RNFL thickness of glaucoma patients particularly in the temporal quadrant may be related to age.