Investigation of the interaction of polyamidoamine dendrimers with nicotinic acid as solubility enhancer / 中国康复理论与实践
Chinese Journal of Rehabilitation Theory and Practice
;
(12): 294-295, 2002.
Article
in English
| WPRIM
| ID: wpr-980690
ABSTRACT
@#ObjectivePolyamidoamine(PAMAM) dendrimers enhance the solubility of nicotinic acid. MethodsPAMAM dendrimers of generation 1 to 6 were prepared and the effect of pH and concentration of the dendrimers on the solubility enhancement of nicotinic acid was investigated. ResultsThe pH and concentration of the dendrimers influence the solubility enhancement of nicotinic acid. Conclusions Electrostatic interaction between the carboxyl group of the nicotinic acid and the amine groups of the dendrimers is involved.
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Index:
WPRIM (Western Pacific)
Language:
English
Journal:
Chinese Journal of Rehabilitation Theory and Practice
Year:
2002
Type:
Article
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