Application and Prospect of Nanopore Sequencing Technology in Etiological Diagnosis of Blood Stream Infection / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 317-321, 2023.
Article
in Chinese
| WPRIM
| ID: wpr-981270
ABSTRACT
Blood stream infection (BSI),a blood-borne disease caused by microorganisms such as bacteria,fungi,and viruses,can lead to bacteremia,sepsis,and infectious shock,posing a serious threat to human life and health.Identifying the pathogen is central to the precise treatment of BSI.Traditional blood culture is the gold standard for pathogen identification,while it has limitations in clinical practice due to the long time consumption,production of false negative results,etc.Nanopore sequencing,as a new generation of sequencing technology,can rapidly detect pathogens,drug resistance genes,and virulence genes for the optimization of clinical treatment.This paper reviews the current status of nanopore sequencing technology in the diagnosis of BSI.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Bacteria
/
Bacteremia
/
Sepsis
/
Blood Culture
/
Nanopore Sequencing
Limits:
Humans
Language:
Chinese
Journal:
Acta Academiae Medicinae Sinicae
Year:
2023
Type:
Article
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