Research progress on the preparation and application of flavonoid nanocrystals / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 338-348, 2023.
Article
in English
| WPRIM
| ID: wpr-982051
ABSTRACT
Flavonoids have been reported to possess significant pharmacological activities,such as antioxidant, anti-inflammatory and anticancer effects. However, the low solubility and low bioavailability limits their clinical application. Nanocrystal technology can solve the delivery problems of flavonoids by reducing particle size, increasing the solubility of insoluble drugs and improving their bioavailability. This article summaries nanosuspension preparation methods and the stabilizers for flavonoid nanocrystals, and reviews the drug delivery routes including oral, Injection and transdermal of flavonoid nanocrystals, to provide information for further research on nanocrystal delivery system of flavonoids.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Particle Size
/
Flavonoids
/
Pharmaceutical Preparations
/
Biological Availability
/
Nanoparticles
/
Anti-Inflammatory Agents
Language:
English
Journal:
Journal of Zhejiang University. Medical sciences
Year:
2023
Type:
Article
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