The experimental study of expression of intercellular adhesion molecule-1 after fluid percussion brain injury / 法医学杂志
Journal of Forensic Medicine
;
(6): 15-18, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-982921
ABSTRACT
OBJECTIVE@#To determine the changes of intercellular adhesion molecule-1 after traumatic brain injury.@*METHODS@#Use the fluid-percussion model to inflict rat brain and take the samples at 2, 4, 8, 12, 24 hours after brain injury. The samples were studied by immunohistochemistry method combined with image analysis by MIAS image analysis system.@*RESULT@#The expression of ICAM-1 upregulates at 2 hours, reaches peak at 12 hours and falls down at 24 hours after brain injury.@*CONCLUSION@#The changes of ICAM-1 in brain can provide a backup for estimation of injury time and survival period after brain injury which sustained within 24 hours.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Percussion
/
Time Factors
/
Image Processing, Computer-Assisted
/
Brain Injuries
/
Rats, Sprague-Dawley
/
Intercellular Adhesion Molecule-1
/
Forensic Medicine
Limits:
Animals
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2002
Type:
Article
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