Apoptosis in mouse after tetramine poisoning / 法医学杂志
Journal of Forensic Medicine
;
(6): 137-143, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-982946
ABSTRACT
OBJECTIVE@#To observe pathological changes and apoptosis in mouse brain, hart, liver and kidney after tetramine poisoning, and to provide some references for forensic identification.@*METHODS@#An experimental model of mouse tetramine poisoning was found, and the technology of apoptosis detection was used. The staining results were analyzed by computer image analysis competitive system.@*RESULTS@#(1) Quantities of apoptosis in brain, hart, liver and kidney in chronic poisoning groups are many more than in acute poisoning groups. As in same organs, Quantities of apoptosis are different after different poisoning time. In addition, the peak-time of apoptosis is not same in different organs. (2) Poison analysis showed that, all organic samples from acute poisoning groups were positive, while that from chronic poisoning groups are negative.@*CONCLUSION@#Chronic tetramine poisoning can not be detective by clinic or poison analysis while can be found changes in apoptosis, which indicate that small amount and chronic poisoning still affects the body.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Poisoning
/
Time Factors
/
Image Processing, Computer-Assisted
/
Brain
/
Bridged-Ring Compounds
/
Cell Count
/
Analysis of Variance
/
Apoptosis
/
Kidney
/
Liver
Limits:
Animals
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2002
Type:
Article
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