Seven Y-specific loci haplotypes and their usefulness in forensic casework / 法医学杂志
Journal of Forensic Medicine
;
(6): 196-200, 2003.
Article
in Chinese
| WPRIM
| ID: wpr-982992
ABSTRACT
OBJECTIVE@#To study genetic polymorphism of 7 Y-specific short tandem repeats (STR) and assess their usefulness in forensic casework.@*METHODS@#7 Y-STR have been amplified in two multiplex reactions, (Multiplex IDYS391, GATA-A4, GATA-A10 and GATA-H4. Multiplex IIDYS439,DYS437 and DYS434). PCR products were separated by polyacrylamide gels electrophoresis followed by silver stain.@*RESULTS@#When 372 unrelated individuals from the Han population in Guangdong were detected by those system, DYS391, GATA-A4, GATA-A10, GATA-H4,DYS439,DYS437 and DYS434 showed 5,7,6,5,6,4,4 alleles, respectively. A total of 254 different haplotypes were identified, of which 201 (79.13%) were found in single individuals. The overall haplotypes diversity reached 0.9960.@*CONCLUSION@#The 7 Y-STR loci are highly genetic polymorphism and they will be very powerful for establishing Y-STR database, understanding human origin, paternity testing and personal identification.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Paternity
/
Polymorphism, Genetic
/
Haplotypes
/
Genetic Markers
/
Polymerase Chain Reaction
/
Sequence Analysis, DNA
/
Microsatellite Repeats
/
Chromosomes, Human, Y
/
Asian People
/
Alleles
Limits:
Humans
/
Male
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2003
Type:
Article
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