A study on the expression of HSP70 and iNOS after human brain contusion / 法医学杂志
Journal of Forensic Medicine
;
(6): 24-26, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-983066
ABSTRACT
OBJECTIVE@#To study the relationship between expression of HSP70, iNOS and traumatic brain contusion (TBI) in different posttraumatic intervals.@*METHODS@#35 samples of brain contusion were examined using immunohistochemecal staining to evaluate the expression of HSP70 and iNOS.@*RESULTS@#Maximal HSP70 expression was found at 0h after brain contusion. The intensity of HSP70 staining decreased remarkably to the minimum at 24h after TBI, then increased gradually. Expression of iNOS positive cells increased significantly and reached the maximum level 48h after TBI, then the expression decreased gradually from the 2nd day to the 11th day.@*CONCLUSION@#The changes of HSP70 and iNOS immunohistochemical staining can be used as a referential data for estimating time interval after human brain contusion.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Staining and Labeling
/
Time Factors
/
Brain
/
Brain Injuries
/
Immunohistochemistry
/
Astrocytes
/
HSP70 Heat-Shock Proteins
/
Nitric Oxide Synthase Type II
/
Neurons
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2005
Type:
Article
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