Detecting the haplotype of three Y-STR loci by fluorescent multiplex amplification / 法医学杂志
Journal of Forensic Medicine
;
(6): 122-124, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-983156
ABSTRACT
OBJECTIVE@#To establish a fluorescent multiplex PCR system for typing Y-STR loci Y-GATA-A7.1, DYS456 and DYS443, and investigate their haplotype frequencies in Chinese Han population.@*METHODS@#203 unrelated males of Han population living in Zhengzhou were typed by fluorescent multiplex amplification system and ABI 3100 genetic analyzer.@*RESULTS@#In Zhengzhou Han population, 5,6 and 6 different alleles were observed for Y-GATA-A7.1, DYS456 and DYS443 loci, and their gene diversity (GD) were 0.669 2, 0.583 9 and 0.705 3 respectively. A total of 44 different haplotypes formed by these three loci was identified and the haplotype diversity (HD) reached 0.952 3.@*CONCLUSION@#The fluorescent multiplex system for these three Y-STR loci will be very powerful for forensic individual identification and paternity testing in Chinese Han population.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Haplotypes
/
Genetic Markers
/
China
/
Polymerase Chain Reaction
/
DNA Fingerprinting
/
DNA Primers
/
Tandem Repeat Sequences
/
Chromosomes, Human, Y
/
Alleles
/
Fluorescence
Limits:
Humans
/
Male
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2006
Type:
Article
Similar
MEDLINE
...
LILACS
LIS