Relationship between the injury time and DNA fragmentation and its quantity in rat brain / 法医学杂志
Journal of Forensic Medicine
; (6): 168-170, 2006.
Article
in Zh
| WPRIM
| ID: wpr-983170
Responsible library:
WPRO
ABSTRACT
OBJECTIVE@#To observe the changes of DNA fragmentation and its quantity along with the time of injury in nerve cells after brain contusion.@*METHODS@#The model of brain contusion caused by free drop hammer was established. TUNEL and Feulgen's DNA staining conjoined with image analysis technique were used for exploration.@*RESULTS@#With the gradually rising of DNA fragmentation, DNA quantity was declining in the brain tissue after contusion.@*CONCLUSION@#TUNEL and Feulgen's DNA staining conjoined with image analysis technique could be utilized in the timing of brain injury and provide a new approach for this issue.
Full text:
1
Index:
WPRIM
Main subject:
Staining and Labeling
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Time Factors
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Brain
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Brain Injuries
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DNA
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Random Allocation
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Rats, Wistar
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Apoptosis
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In Situ Nick-End Labeling
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Forensic Pathology
Limits:
Animals
Language:
Zh
Journal:
Journal of Forensic Medicine
Year:
2006
Type:
Article