Haplotypes of DXS10011 and DXS8377 in Guangdong Han individuals / 法医学杂志
Journal of Forensic Medicine
;
(6): 207-209, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-983182
ABSTRACT
OBJECTIVE@#To investigate genetic polymorphism of two X chromosome specific STR DXS10011 and DXS8377 in male samples from Guangdong Han population.@*METHODS@#The DNA samples were amplified by PCR and analyzed by polyacrylamide gel electrophoresis followed by silver staining.@*RESULTS@#Among 113 samples, 20 alleles were found for DXS1011 and 12 alleles for DXS8377. Also, 72 DXS10011-DXS8377 haplotypes were shown. The most common haplotypes only occurred three times. When only female children were tested in motherless case, the exclusion probability of paternity was 0.9588 for DXS10011-DXS8377 haplotypes. Investigations in 83 family trios with female children and 29 pedigrees with two children suggested a co-dominant X-linked inheritance; mutations were not found.@*CONCLUSION@#Our data indicate that DXS10011 and DXS8377 are highly informative X chromosome markers for complicated kinship analysis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Paternity
/
Polymorphism, Genetic
/
Haplotypes
/
DNA
/
China
/
Polymerase Chain Reaction
/
Tandem Repeat Sequences
/
Chromosomes, Human, X
/
Forensic Sciences
/
Asian People
Limits:
Humans
/
Male
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2006
Type:
Article
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