Immunohistochemical study on contents of beta-amyloid, alpha-actin and collagen IV in cerebral small vessels with unknown type of pathological lesion / 法医学杂志
Journal of Forensic Medicine
;
(6): 413-416, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-983236
ABSTRACT
OBJECTIVE@#To investigate the structural characteristics of the cerebral small vessels with an unknown type of pathological lesion (UTPL).@*METHODS@#Contents of beta-amyloid, alpha-actin and collagen IV in cerebral small vessels with UTPL were studied by Congo red staining, immunohistochemical staining and computer image analysis.@*RESULTS@#The low expression levels of alpha-actin and collagen IV (P<0.05) were observed in tunica media of the vessels with UTPL, and no positive expression of beta-amyloid (P>0.05) was observed in these vessel walls. The expressions of proteins mentioned above in UTPL were different from those of cerebral amyloid angiopathy(CAA) and hyaline arteriolosclerosis.@*CONCLUSION@#UTPL was different from CAA or hyaline arteriolosclerosis in pathologic feature.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Autopsy
/
Staining and Labeling
/
Subarachnoid Hemorrhage
/
Blood Vessels
/
Image Processing, Computer-Assisted
/
Brain
/
Immunohistochemistry
/
Amyloid beta-Peptides
/
Actins
/
Cerebral Amyloid Angiopathy
Limits:
Humans
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2006
Type:
Article
Similar
MEDLINE
...
LILACS
LIS