Bcl-2 expression following the brain concussion in rats / 法医学杂志
Journal of Forensic Medicine
;
(6): 18-19, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-983254
ABSTRACT
OBJECTIVE@#To evaluate the expression of Bcl-2 protein after brain concussion.@*METHODS@#Expression levels of Bel-2 protein in cortex, pontine and cerebellum of rats were investigated using immunohistochemistry.@*RESULTS@#There was no expression of Bcl-2 protein in control group seen. The expression of Bcl-2 protein in brain concussion groups was detected at l hour, and the expression level reached its peak 4 days after the concussion and then declined gradually.@*CONCLUSION@#Our findings suggest that the detection of Bel-2 protein could be an indicator for diagnosis of brain concussion and for estimation of the post injury time interval.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Time Factors
/
Brain
/
Brain Concussion
/
Brain Stem
/
Immunohistochemistry
/
Cerebral Cortex
/
Rats, Sprague-Dawley
/
Proto-Oncogene Proteins c-bcl-2
/
Contusions
/
Disease Models, Animal
Limits:
Animals
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2007
Type:
Article
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