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Validation the haplotype polymorphisms of the DXS7424-DXS101 on X-chromosome / 法医学杂志
Journal of Forensic Medicine ; (6): 342-344, 2007.
Article in Chinese | WPRIM | ID: wpr-983315
ABSTRACT
OBJECTIVE@#To validate the genetic characteristics and distribution of DXS7424-DXS101 on X chromosome in Han population.@*METHODS@#DXS7424 and DXS101 loci were genotyped by PCR, PAGE and silvers stain methods. Their genetic parameters were analyzed by Arlequin software.@*RESULTS@#There were 37 haplotypes detected in 151 Han unrelated males. The frequencies ranged from 0.0066 to 0.1391, with a GD value of 0.9453 and a DP value of 0.9389. Haplotypes 16-23 were the most common haplotypes in Han population.@*CONCLUSION@#Analysis of combined DXS7424 and DXS101 haplotypes appears to be a powerful means in population genetics and forensic practice for determination of identity and paternity.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Polymorphism, Genetic / Haplotypes / China / Polymerase Chain Reaction / Tandem Repeat Sequences / Chromosomes, Human, X / Alleles / Gene Frequency / Genetics, Population / Genetic Linkage Limits: Humans / Male Country/Region as subject: Asia Language: Chinese Journal: Journal of Forensic Medicine Year: 2007 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Polymorphism, Genetic / Haplotypes / China / Polymerase Chain Reaction / Tandem Repeat Sequences / Chromosomes, Human, X / Alleles / Gene Frequency / Genetics, Population / Genetic Linkage Limits: Humans / Male Country/Region as subject: Asia Language: Chinese Journal: Journal of Forensic Medicine Year: 2007 Type: Article