Application of D6S1043 and D12S391 loci in forensic paternity testing / 法医学杂志
Journal of Forensic Medicine
;
(6): 345-346, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-983316
ABSTRACT
OBJECTIVE@#The aim was to investigate the polymorphisms of D6S1043 and D12S391 loci among Han population and evaluate their values in paternity testing. MERTHODS By using fluorescence dye-labeled primers and capillary electrophoresis, the allele frequencies of the two STR loci among 192 unrelated individuals were investigated.@*RESULTS@#Twelve alleles were observed in both D6S1043 and D12S391 loci. The ranges of allele frequencies were from 0.0026 to 0.1719 and from 0.0026 to 0.2292, respectively. The discrimination power of D6S1043 and D12S391 were 0.9656 and 0.9510. The Average exclusion probability in paternity testing for duos were 0.573 and 0.510. The Average exclusion probability in paternity testing for trios were 0.731 and 0.679, respectively. The genotypes frequencies met Hardy-Weinberg equilibrium expectation.@*CONCLUSION@#The results show that D6S1043 and D12S391 have high values in forensic paternity testing.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Paternity
/
China
/
Probability
/
DNA Fingerprinting
/
Electrophoresis, Capillary
/
Tandem Repeat Sequences
/
Alleles
/
Forensic Medicine
/
Gene Frequency
/
Genetics, Population
Limits:
Humans
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2007
Type:
Article
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