Distribution of tryptophan hydroxylase gene-T457C locus polymorphism in Han ethnic group in northern China / 法医学杂志
Journal of Forensic Medicine
;
(6): 444-445, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-983337
ABSTRACT
OBJECTIVE@#To study the distribution of the tryptophan hydroxylase (TPH) gene-T457C locus polymorphism in Han ethnic group in northern China and to find its applicable value in forensic science.@*METHODS@#Genomic DNA samples, extracted from 180 unrelated individuals in northern Chinese Han population, were analyzed by PCR-RFLP.@*RESULTS@#The discrimination power (DP) value and the power of exclusion (PE) value of the TPH gene-T457C locus were 0.624 and 0.187, respectively. The allele frequency showed significant difference from that of French people (P=0.04).@*CONCLUSION@#Polymorphism of the TPH gene-T457C locus could show ethnic and regional differences. It has a potential to be used in forensic science.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Polymorphism, Genetic
/
Tryptophan Hydroxylase
/
China
/
Polymerase Chain Reaction
/
Sequence Analysis, DNA
/
Asian People
/
Electrophoresis, Polyacrylamide Gel
/
Alleles
/
Gene Frequency
/
Genotype
Limits:
Humans
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2007
Type:
Article
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