Acute necrotizing pancreatitis and postmortem autolysis of pancreas / 法医学杂志
Journal of Forensic Medicine
; (6): 94-101, 2008.
Article
in Zh
| WPRIM
| ID: wpr-983359
Responsible library:
WPRO
ABSTRACT
OBJECTIVE@#To compare the pathomorphologic changes between the pancreas in acute necrotizing pancreatitis (ANP) and that in acute deaths of rats (within 48 hours) so as to find the distinctions.@*METHODS@#The animal models of ANP and other acute deaths (electroshock, mechanic asphyxia/strangle, and acute poisoning with tetramine) were established according to the criteria. Half-quantitative grading and image quantitative analysis methods were employed to observe the gross and microscopic changes of the pancreases.@*RESULTS@#Three features including inflammation infiltrate, fat necrosis and calcium deposit in the ANP group were considerably different from that in other acutely died rat group (P<0.05).@*CONCLUSION@#Inflammation infiltrate, fat necrosis and calcium deposit are the most important pathologic features found in ANP by common light microscope, distinguishing ANP from postmortem pancreatic autolysis.
Full text:
1
Index:
WPRIM
Main subject:
Pancreas
/
Poisoning
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Postmortem Changes
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Autolysis
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Rats, Sprague-Dawley
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Pancreatitis, Acute Necrotizing
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Forensic Pathology
Limits:
Animals
Language:
Zh
Journal:
Journal of Forensic Medicine
Year:
2008
Type:
Article