The expressions of HSP 70 mRNA and c-fos mRNA in the skeletal muscle and cardiac muscle of rabbits by electrocuted / 法医学杂志
Journal of Forensic Medicine
;
(6): 245-251, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-983386
ABSTRACT
OBJECTIVE@#To study the changes of HSP 70 mRNA and c-fos mRNA expression and to find a method to differentiate antemortem from postmortem electrocution.@*METHODS@#Fifteen New Zealand rabbits were randomly divided into three groups, the antemortem electrocution group, the postmortem electrocution group, and the control group. Each group consists of five rabbits. The levels of HSP 70 mRNA and c-fos mRNA in skeletal muscle and cardiac muscle were examined with quantitative fluorescent RT-PCR.@*RESULTS@#The levels of HSP 70 mRNA and c-fos mRNA in the antemortem electrocution group increased significantly (P<0.05), compared with that of the postmortem electrocution group.@*CONCLUSION@#The changes of HSP 70 mRNA and c-fos mRNA expression in skeletal muscle and cardiac muscle can be used as an indicator to distinguish antemortem from postmortem electrocution.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Postmortem Changes
/
RNA, Messenger
/
Random Allocation
/
Proto-Oncogene Proteins c-fos
/
Muscle, Skeletal
/
HSP70 Heat-Shock Proteins
/
Forensic Pathology
/
Electric Injuries
/
Myocardium
Limits:
Animals
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2008
Type:
Article
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