Expression of Bcl-2 and Bax proteins in myocardial cells after Macleaya cordata alkaloids poisoning in rats / 法医学杂志
Journal of Forensic Medicine
;
(6): 246-253, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-983479
ABSTRACT
OBJECTIVE@#To observe the expression of Bcl-2 and Bax proteins in rat's myocardial cells after Macleaya cordata alkaloids poisoning, and to provide certain molecular biology references for the detection of Macleaya cordata alkaloids poisoning.@*METHODS@#Experimental model of Macleaya cordata alkaloids poisoning was established, the expression levels of Bcl-2 and Bax proteins in these cells were detected by immunohistochemistry, and the results were analyzed by computer image system.@*RESULTS@#The expression levels of Bcl-2 and Bax proteins in myocardial cells in poisoning groups were much greater than those in the control groups (P<0.05).@*CONCLUSION@#If the clinical symptoms may not be obvious, the detection of Bcl-2 and Bax proteins level by immunohistochemistry still could be ancillary method.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Papaverine
/
Staining and Labeling
/
Time Factors
/
Immunohistochemistry
/
Rats, Sprague-Dawley
/
Proto-Oncogene Proteins c-bcl-2
/
Papaveraceae
/
Myocytes, Cardiac
/
Disease Models, Animal
/
Bcl-2-Associated X Protein
Limits:
Animals
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2009
Type:
Article
Similar
MEDLINE
...
LILACS
LIS