The value of TNFalpha testing in evaluation of death due to drug anaphylactic shock / 法医学杂志
Journal of Forensic Medicine
;
(6): 332-333, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-983495
ABSTRACT
OBJECTIVE@#To analyze the changes of the serum TNFalpha level in cadavers of drug anaphylactic shock(DAS) and to explore the significance of the TNFalpha testing in evaluation of death caused by DAS.@*METHODS@#The level of serum TNFalpha from cardiac blood was determined by double antibody-sandwich ELISA method.@*RESULTS@#The level of TNFalpha in the experimental group was (131.6+/-9.4) pg/mL, while the level in the infectious diseases control group and the normal control group were (87.3+/-6.4) pg/mL and (17.2+/-4.5) pg/mL, respectively. There was statistically significant difference among the groups (P<0.05).@*CONCLUSION@#The serum TNFalpha level may be used as one of the indexes for evaluation of death caused by highly suspected drug anaphylactic shock.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Autopsy
/
Enzyme-Linked Immunosorbent Assay
/
Cause of Death
/
Tumor Necrosis Factor-alpha
/
Forensic Pathology
/
Drug Hypersensitivity
/
Anaphylaxis
Limits:
Adolescent
/
Adult
/
Aged
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2009
Type:
Article
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