The influence of estazolam on human neurobehavioral function / 法医学杂志
Journal of Forensic Medicine
;
(6): 30-32, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-983534
ABSTRACT
OBJECTIVE@#To study the relation between human blood estazolam concentration and neurobehavioral function.@*METHODS@#The neurobehavioral ability of 10 volunteers were measured with computer-administered neurobehavioral evaluation system-chinese3 (NES-C3) and SMART EquiTest system.@*RESULTS@#The neurobehavioral ability and balance function declined 1 h later after dosing estazolam. The neurobehavioral ability index and balance function declined to the lowest level 3 h later after dosing estazolam. The neurobehavioral ability recovered partly 6 h later after dosing estazolam, and neurobehavioral ability recovered completely 10 h later.@*CONCLUSION@#Driving ability was impaired when estazolam concentration in blood is 20 ng/mL, and the neurobehavioral ability declined when estazolam concentration is 40 ng/mL in blood. The influence to human in absorption process is greater than the metabolic process with the same estazolam concentration.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Psychomotor Performance
/
Reaction Time
/
Attention
/
Behavior
/
Accidents, Traffic
/
Administration, Oral
/
Estazolam
/
Anticonvulsants
/
Neuropsychological Tests
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2010
Type:
Article
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