Applications of Alu family in forensic DNA analysis / 法医学杂志
Journal of Forensic Medicine
;
(6): 47-50, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-983539
ABSTRACT
Alu family is the primate specific short interspersed repetitive elements (SINEs). Its abundance and diversity distribution in genome, high methylation level and polymorphic for insertion make them ideally suitable as tools in forensic applications. The application of A4 lu sequence in forensic genomics, include DNA quantitation, race determination, species and gender identification, personal identification, paternity testing and whole-genome amplification. The principles and characteristics of these Alu-based techniques are also summarized. The prospect of Alu as forensic molecular marker is discussed as well.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Polymorphism, Genetic
/
DNA
/
Base Sequence
/
Genetic Markers
/
Genome, Human
/
Polymerase Chain Reaction
/
Chromosomes, Human
/
Sensitivity and Specificity
/
Sequence Analysis, DNA
/
DNA Methylation
Limits:
Humans
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2010
Type:
Article
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