Gastric Adenocarcinoma with Coexistent Hepatoid Adenocarcinoma and Neuroendocrine Carcinoma: A Case Report
Korean Journal of Pathology
;
: 79-82, 2009.
Article
in English
| WPRIM
| ID: wpr-9836
ABSTRACT
This report represents a very rare case of a gastric adenocarcinoma that was coexistent with hepatoid adenocarcinoma and neuroendocrine carcinoma. A 77-year-old man was admitted to our hospital due to a huge ulcerofungating mass identified at the proximal body of the stomach. After a pathological diagnosis of the tumor as a poorly differentiated adenocarcinoma was made, the patient underwent a total gastrectomy with lymph node dissection. Microscopically, the tumor consisted of three morphologically distinct components-tubular adenocarcinoma, hepatoid adenocarcinoma and neuroendocrine carcinoma. The hepatoid adenocarcinoma component resembled a hepatocellular carcinoma and produced alpha-fetoprotein. The neuroendocrine carcinoma component was positive for chromogranin and synaptophysin immunostains. This is an example of the diverse morphological and immunophenotypical differentiation of gastric carcinomas.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Stomach
/
Stomach Neoplasms
/
Adenocarcinoma
/
Alpha-Fetoproteins
/
Synaptophysin
/
Carcinoma, Neuroendocrine
/
Carcinoma, Hepatocellular
/
Gastrectomy
/
Lymph Node Excision
Limits:
Aged
/
Humans
Language:
English
Journal:
Korean Journal of Pathology
Year:
2009
Type:
Article
Similar
MEDLINE
...
LILACS
LIS