Application of nucleic acids and proteins in estimation of postmortem interval / 法医学杂志
Journal of Forensic Medicine
;
(6): 50-53, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-983627
ABSTRACT
Accurate estimation of postmortem interval (PMI) is one of the most important and difficult issues in forensic medicine. After death, the tissues autolyze and biomacromolecules degrade. DNA concentration decreases gradually with linear relationship with PMI. The housekeeping gene mRNA, for example beta-actin, GAPDH, has certain stability and can be used to PMI estimation as internal standard. This paper reviews the research progress and problems about DNA, RNA and proteins in the estimation of PMI in order to provide guidance for forensic pathology.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Postmortem Changes
/
Temperature
/
Time Factors
/
Brain
/
DNA
/
RNA, Messenger
/
Nucleic Acids
/
Proteins
/
Actins
/
Spectroscopy, Fourier Transform Infrared
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2011
Type:
Article
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