The role and significance of microRNA in human cardiovascular disease and forensic science

Li-Liang LI; Zi-Qin ZHAO

The role and significance of microRNA in human cardiovascular disease and forensic science / 法医学杂志

Li-Liang LI; Zi-Qin ZHAO.

Journal of Forensic Medicine ; (6): 39-42, 2013.

Article in Chinese | WPRIM | ID: wpr-983792

ABSTRACT

ABSTRACT

microRNA (miRNA or miR) is a small single stranded non-coding RNA (21-25nt) that regulates gene expression in almost creatures. Currently, plenty of researches on how miRNA affects human cardiovascular disease have been reported. This review highlights recent findings about the role of miRNA in heart tissue and circulation correlated with human cardiovascular disease and explores the application of miRNA in sudden cardiac death in forensic science.

Subject(s)

Animals; Humans; Biomarkers/blood; Cardiomyopathy, Dilated/metabolism; Cardiovascular Diseases/metabolism; Cause of Death; Death, Sudden, Cardiac/pathology; Forensic Sciences/methods; Gene Expression Profiling; Gene Expression Regulation; Heart Failure/metabolism; MicroRNAs/metabolism; Myocardium/pathology; Pulmonary Embolism/diagnosis; Up-Regulation

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pulmonary Embolism / Cardiomyopathy, Dilated / Biomarkers / Cardiovascular Diseases / Up-Regulation / Gene Expression Regulation / Cause of Death / Death, Sudden, Cardiac / Gene Expression Profiling / MicroRNAs Limits: Animals / Humans Language: Chinese Journal: Journal of Forensic Medicine Year: 2013 Type: Article

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