Time-related expression of IL-6, IL-8 and TNF-alpha following explosive injury to rabbit's chest / 法医学杂志
Journal of Forensic Medicine
;
(6): 85-87, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-983885
ABSTRACT
OBJECTIVE@#To explore the relationship between the expression changes of cytokines, interleukin-6 (IL-6), interleukin-8(IL-8), and tumor necrosis factor-alpha (TNF-alpha), and the wound time following explosive injury to rabbit's chest.@*METHODS@#The rabbit's model of explosive injury was established. The expression levels of IL-6, IL-8 and TNF-alpha in the plasma were detected by ELISA method at different wound time (0.5-12h).@*RESULTS@#The level of IL-6 increased at 3h after wounding and reached peak at 6 h. The level of IL-8 increased at 1 h and reached peak at 6 h. The level of TNF-alpha increased at 0.5 h and reached peak at 3 h.@*CONCLUSION@#IL-6, IL-8 and TNF-alpha have a time-related expression after explosive injury.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Thoracic Injuries
/
Enzyme-Linked Immunosorbent Assay
/
Interleukin-8
/
Interleukin-6
/
Tumor Necrosis Factor-alpha
/
Explosions
Limits:
Animals
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2014
Type:
Article
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