Allele-specific PCR and its application in forensic science / 法医学杂志
Journal of Forensic Medicine
;
(6): 282-287, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-983921
ABSTRACT
Allele-specific polymerase chain reaction (AS-PCR) is a technique based on allele-specific primers, which can be used to analyze single nucleotide polymorphism (SNP) effectively including the transition, transversion and insertion/deletion polymorphism and has been exploited in the study of diseases research, molecular diagnosis, and forensic biological evidence. The article systematically reviews the principle, the detection methods, improvement of AS-PCR, and its research updates in the fields of autosome, Y chromosome and mitochondrial SNP, as well as its application in forensic science.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Polymorphism, Genetic
/
Polymerase Chain Reaction
/
DNA Primers
/
Polymorphism, Single Nucleotide
/
Forensic Sciences
/
Alleles
Limits:
Humans
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2014
Type:
Article
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