Genetic polymorphism of nine non-CODIS STR loci in Hunan Province-based Chinese Han population / 法医学杂志
Journal of Forensic Medicine
;
(6): 441-445, 2014.
Article
in English
| WPRIM
| ID: wpr-983946
ABSTRACT
OBJECTIVE@#To determine the allelic frequency distribution and genetic parameters of nine non-CODIS DNA index systems of the short tandem repeat (STR) loci (D2S1772, D6S1043, D7S3048, D8S1132, D11S2368, D12S391, D13S325, D18S1364, and GATA198B05).@*METHODS@#A total of 353 blood samples were collected, extracted, amplified, and analyzed from unrelated healthy individuals of Han nationality in Hunan Province, China.@*RESULTS@#One hundred and fourteen alleles were observed in the population with corresponding allelic frequencies ranged from 0.001 0 to 0.323 0. For all the nine non-CODIS STR loci, the observed genotypic data showed no significant deviations from the Hardy-Weinberg equilibrium. The Ho, He, PIC, DP, and PE of the studied non-CODIS STR loci ranged from 0.1080 to 0.1950, 0.8050 to 0.8920, 0.7700 to 0.8600, 0.9250 to 0.9660 and 0.6070 to 0.7800, respectively.@*CONCLUSION@#Nine non-CODIS STR loci have high degrees of polymorphisms, which may be useful in individual forensic identification and parentage testing in forensic practice.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Polymorphism, Genetic
/
Ethnicity
/
China
/
Microsatellite Repeats
/
Asian People
/
Alleles
/
Gene Frequency
/
Genetics, Population
/
Genotype
Limits:
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Journal of Forensic Medicine
Year:
2014
Type:
Article
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