Efficacy of psychological intervention on improving mental health status among patients with schizophrenia during rehabilitation in China： a Meta-analysis / 四川精神卫生

ABSTRACT

ObjectiveTo systematically evaluate the efficacy of psychological intervention on the mental health status of schizophrenia during rehabilitation in China， so as to provide references for the implementation of effective psychological intervention for patients. MethodsCochrane Library， PubMed， Web of Science， Chinese Biomedical Literature Database， CNKI， Wanfang Database and VIP Database were retrieved for the randomized controlled trials （RCTs） related to the psychological intervention for patients with schizophrenia during rehabilitation in China published from the inception to December 2021. After the assessment of risk of bias in literatures included， Meta-analysis was performed by using RevMan 5.4.1 software. ResultsA total of 1 211 subjects in 13 RCTs were enrolled， including 602 cases in the control group and 609 in the intervention group. Meta-analysis denoted that intervention group had lower scores of Symptom Checklist 90 （SCL-90） （WMD=-15.41， 95% CI：-18.67~-12.16， P<0.01）， Self-rating Depression Scale （SDS） （WMD=-9.07， 95% CI：-10.38~-7.77， P<0.01） and Self-rating Anxiety Scale （SAS） （WMD=-7.47， 95% CI：-9.85~-5.10， P<0.01） than those of control group after intervention， and the difference was statistically significant. ConclusionApplication of psychological intervention based on drug therapy has certain efficacy on improving mental health status in patients with schizophrenia during rehabilitation in China.