The Relationship of the Estimates of Effective Concentration Calculated by Logit, Probit, and Sigmoid Emax / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 345-347, 2002.
Article
in Korean
| WPRIM
| ID: wpr-98769
ABSTRACT
BACKGROUND:
This study is to demonstrate that the estimates of effective concentration (EC) inferred by logit, probit, and sigmoid Emax can be declared to be similar.METHODS:
The estimates of EC (5, 25, 50, 75, 95 [%]) of 24 vecuronium concentration-single twitch response data were obtained with three pharmacodynamic methods. A paired t-test with Bonferroni's correction was used.RESULTS:
The distribution of estimates by probit were narrower than that of those by logit and sigmoid Emax. The estimates of logit and sigmoid Emax were closely similar.CONCLUSIONS:
It suggests that the EC estimates of other paper analysed by the different pharmacodynamic method could be lower or higher.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Colon, Sigmoid
/
Vecuronium Bromide
Language:
Korean
Journal:
Korean Journal of Anesthesiology
Year:
2002
Type:
Article
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