Metabolic Syndrome and Risk of Gastric Cancer: A Meta-analysis / 肿瘤防治研究

ABSTRACT

Objective To evaluate the relation between metabolic syndrome (MetS) and gastric cancer (GC) based on a meta-analysis. Methods The case-control studies about the relation between MetS and GC were retrieved from CNKI, WanFang Data, VIP, CBM, Web of Science, The Cochrane Library and PubMed database. The retrieval time was from inception to June, 2020. Two researchers independently screened the literatures, extracted the data and evaluated the quality of the included studies. The meta-analysis of the included literatures was conducted by the Stata 12.0 software. Results A total of six literatures, involving 43617 participants, were included. The results of meta-analysis showed that there was no statistically significant difference between GC and non-GC groups in the risk of hyperglycemia (OR=1.24, 95%CI 0.59-2.61), hypertension (OR=1.40, 95%CI 0.60-3.25) or MetS (OR=0.79, 95%CI 0.44-1.39), respectively. Conclusion MetS may not be related to the risk of GC.