Progress of T-cell immunodeficiency and immunotherapy in chronic lymphocytic leukemia / 白血病·淋巴瘤
Journal of Leukemia & Lymphoma
;
(12): 439-442, 2023.
Article
in Chinese
| WPRIM
| ID: wpr-989004
ABSTRACT
The occurrence and development of chronic lymphocytic leukemia (CLL) are related to many factors such as CLL cells, defective T cells and tumor microenvironment. The mutual interaction between tumor cells and immune cells in tumor microenvironment is an important factor for the progress of CLL. T cells, as the main members of adaptive immunity, play an ambiguous role in CLL. This review focuses on the immunodeficiency of T-cell subsets in CLL and recent advances in T-cell immunotherapy, in order to explore the potential role of T cells in the occurrence, development and outcome of CLL.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Leukemia & Lymphoma
Year:
2023
Type:
Article
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