Two Cases of Allergic Reactions to Mesna which Imitate Malar Rash / 대한류마티스학회지
The Journal of the Korean Rheumatism Association
;
: 196-199, 2000.
Article
in Korean
| WPRIM
| ID: wpr-9891
ABSTRACT
Hemorrhagic cystitis is potentially life-threatening sequellae of chemotherapy using oxazaphosphorine alkylating agents (cyclophosphamide and ifosfamide). Mesna contains a sulfhydryl group that is believed to bind acrolein within the urinary collecting system and reduce the hemorrhagic cystitis without affecting the chemotherapeutic potential. To date, about thirty cases of hypersensitivity or allergic reactions of the delayed and urticarial type associated with mesna have been reported. We reported two patients with systemic lupus erythematosus who developed facial rash and flushing associated with mesna which imitate malar rash.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Acrolein
/
Mesna
/
Cyclophosphamide
/
Cystitis
/
Drug Therapy
/
Alkylating Agents
/
Exanthema
/
Flushing
/
Hypersensitivity
/
Lupus Erythematosus, Systemic
Limits:
Humans
Language:
Korean
Journal:
The Journal of the Korean Rheumatism Association
Year:
2000
Type:
Article
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