Predictors of outcome after endovascular therapy in patients with acute basilar artery occlusion / 国际脑血管病杂志

ABSTRACT

Objective:To investigate the predictors of outcome after endovascular therapy in patients with acute basilar artery occlusion (ABAO).Methods:Patients with ABAO received EVT in Bozhou People’s Hospital from May 2019 to September 2022 were included prospectively. The demographic data, clinical data, relevant parameters of periprocedural period and follow-up data were collected. The outcome evaluation was performed at 90 d after procedure. The modified Rankin Scale score ≤3 was defined as good outcome, and >3 was defined as poor outcome. Multivariate logistic regression analysis was used to determine the independent influencing factors of good outcome after EVT. Results:A total of 42 patients with ABAO were included, 21 (50%) had a good outcome and 21 had a poor outcome. There were significant differences in the National Institutes of Health Stroke Scale (NIHSS), posterior circulation Alberta Stroke Program Early CT Score (pc-ASPECTS), the time from onset to recanalization, the proportion of patients with successful recanalization, use of remedial treatment, and complications were statistically significant in both groups (all P<0.05). Multivariate logistic regression analysis showed that after adjusting for other risk factors, the low NIHSS score (odds ratio [ OR] 0.756, 95% confidence interval [ CI] 0.615-0.903; P=0.008), less use of remedial treatment measures ( OR 0.170, 95% CI 0.033-0.884; P=0.035) and high pc-ASPECTS ( OR 4.274, 95% CI 1.418-12.882; P=0.010) were the independent predictors of good outcomes. Conclusions:Half of the patients with ABAO have a good outcome after EVT. Low NIHSS score, high pc-ASPECTS at admission and less use of remedial measures are the independent predictors of good outcomes in patients with ABAO.