Research status and application prospect of a novel immune checkpoint TIGIT in the immunotherapy of multiple myeloma / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 122-125, 2023.
Article
in Chinese
| WPRIM
| ID: wpr-989533
ABSTRACT
T cell immunoglobulin and immunoreceptor tyrosine-based inhibitory motif domain (TIGIT) is a new immune checkpoint protein. Studies have shown that TIGIT can cause dysfunction of immune cells, weaken the anti-tumor effect, thus leading to tumor immune tolerance and immune escape. Blocking TIGIT can reverse immune cell failure and exert anti-tumor effect, which is expected to become a new therapeutic target for multiple myeloma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2023
Type:
Article
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