Morbidity of Solid Cancer in Behcet's Disease: Analysis of 11 Cases in a Series of 506 Patients
Yonsei Medical Journal
;
: 895-901, 2013.
Article
in English
| WPRIM
| ID: wpr-99048
ABSTRACT
PURPOSE:
Behcet's disease (BD) is rarely reported to be associated with malignancies in the literature. However, the frequency of cancer in BD patients remains unknown. This study evaluated cancer morbidity in BD patients compared with that in the general population of Korea. MATERIALS ANDMETHODS:
A retrospective chart review was performed on 506 patients visiting our hospital from 1994 to 2011 for BD. We analyzed the standardized morbidity rate (SMR), which is the ratio of observed to expected malignancies. Furthermore, we reviewed cases of solid cancer in BD patients in the literature.RESULTS:
Of the 506 patients with BD, 11 (2.17%) developed cancer. We found a variety of solid cancers without predominance and no hematologic malignancies. The total number of cancers observed was less than expected, which was determined from the statistical data of the National Cancer Information Center of Korea, with an SMR of 0.023 (95% confidence interval, 0.012-0.039).CONCLUSION:
BD may be associated with a lower cancer-related morbidity compared with the general population of Korea.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Behcet Syndrome
/
Retrospective Studies
/
Follow-Up Studies
/
Republic of Korea
/
Neoplasms
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Yonsei Medical Journal
Year:
2013
Type:
Article
Similar
MEDLINE
...
LILACS
LIS