Relationship between QRS-T angle and R/T ratio on electrocardiograms and cardiac function and major adverse cardiac events in patients with coronary heart disease / 中国基层医药

ABSTRACT

Objective:To analyze the relationship between QRS-T angle and R/T ratio on electrocardiograms and cardiac function and major adverse cardiac events (MACEs) in patients with coronary heart disease, evaluate cardiac function in patients with coronary heart disease, and investigate the optimal method to predict the occurrence of MACEs.Methods:A total of 80 patients with coronary heart disease who were admitted to the Affiliated People's Hospital of Ningbo University from January 2019 to May 2022 were included in this study. Their cardiac function was evaluated. QRS-T angle and R/T ratio on electrocardiograms were compared among patients. The relationship between the QRS-T angle and R/T ratio on electrocardiograms and cardiac function in patients with chronic heart disease was analyzed using Spearman's correlation coefficient. All patients received 1 week of standardized treatment. These patients were divided into a MACE group and a non-MACE group according to whether they had a MACE. Univariate and multivariate logistic regression analyses were performed to determine the association of QRS-T angle and R/T ratio on electrocardiograms with the occurrence of MACE in patients with coronary heart disease.Results:The QRS-T angle and R/T ratio on electrocardiograms in patients with New York Heart Association (NYHA) class IV heart failure were (115.75 ± 6.83)° and (4.95 ± 0.89) respectively, which were significantly higher than those in patients with NYHA class II and III heart failure (both P < 0.05). The QRS-T angle and R/T ratio on electrocardiograms in patients with NYHA class III heart failure were higher than those in patients with NYHA class II heart failure (both P < 0.05). Spearman correlation coefficient analysis results showed that the QRS-T angle and R/T ratio on electrocardiograms were positively correlated with NYHA cardiac function classification (both P < 0.05). Univariate logistic regression analysis results showed that low left ventricular ejection fraction, high NYHA class, low-density lipoprotein level, large QRS-T angle, and R/T ratio were the risk factors for developing a MACE in patients with chronic heart disease (all P < 0.05). Conclusion:QRS-T angle and R/T ratio on electrocardiograms increase with the worsening of cardiac function, which is a risk factor for developing a MACE in patients with chronic heart disease. It can be used as an objective and effective factor to evaluate the actual condition of patients in the early diagnosis and treatment of chronic heart disease and provide data support for reasonably optimizing intervention strategies and improving therapeutic effects.