Clinical status and research progress of primary pulmonary mucinous adenocarcinoma / 中国综合临床
Clinical Medicine of China
; (12): 261-265, 2023.
Article
in Zh
| WPRIM
| ID: wpr-992501
Responsible library:
WPRO
ABSTRACT
Primary pulmonary mucinous adenocarcinoma is a subtype of lung adenocarcinoma, and its epidemiology is similar to other pulmonary adenocarcinoma. Because of its low incidence rate, the survival data of patients with pulmonary mucinous adenocarcinoma are few and often contradictory. KRAS mutations often occur in pulmonary mucinous adenocarcinoma, but EGFR mutations are rare. The expression of PD-L1 in pulmonary mucinous adenocarcinoma is very low. Patients with early pulmonary mucinous adenocarcinoma can benefit from surgery. Lobectomy is still the standard operation at present, but sub lobectomy may also be effective for early pulmonary mucinous adenocarcinoma. Other treatment options include platinum based dual drug chemotherapy, targeted therapy targeting driving genes, and the recent rise of immunotherapy. Future new targets and corresponding treatments should require more research to confirm.
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WPRIM
Language:
Zh
Journal:
Clinical Medicine of China
Year:
2023
Type:
Article