A case of POEMS syndrome associated with amyloidosis / 대한내과학회지
Korean Journal of Medicine
;
: 425-431, 2004.
Article
in Korean
| WPRIM
| ID: wpr-99260
ABSTRACT
POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal M protein, and skin lesion) is a rare multisystemic disease of unknown cause with varying clinical manifestations. Amyloidosis-associated POEMS Syndrome is also rare condition. We experienced a 63-year-old female who had been suffered from edema and tingling sensation of low extremities. She also had a marked demyelination, axonal degeneration and regeneration of the nerve, hypoaldosteronism, hyperprolactinemia, decreased sexual hormone, monoclonal gammopathy (IgG lambda type), skin change and ascites. The renal biopsy revealed homogenous mesangial widening with a few cell nuclei at the glomerular capillary, and it showed positive apple-green birefringence in Congo-red stain. It's the first report that shows the deposition of amyloid in patients with POEMS syndrome in Korea. Edema and M-spike were improved by use of prednisolone, melphalan, fludrocortisone and colchicine.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Paraproteinemias
/
Ascites
/
Regeneration
/
Sensation
/
Skin
/
Axons
/
Biopsy
/
Birefringence
/
Hyperprolactinemia
/
Capillaries
Limits:
Female
/
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2004
Type:
Article
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