A Case of Collapsing Glomerulopathy Discovered in End Stage Renal Disease(ESRD) with Normal Sized Kidney / 대한신장학회잡지
Korean Journal of Nephrology
; : 1026-1030, 2001.
Article
in Ko
| WPRIM
| ID: wpr-99331
Responsible library:
WPRO
ABSTRACT
Collapsing glomerulopathy is recently described as the disease which causes rapidly progressive renal failure. Clinically, the disease starts with constitutional symptoms, and then nephrotic syndrome with marked proteinuria and hypertension follows. Eventually the disease rapidly progresses to the ESRD within several weeks to months. Its typical renal biopsy findings are extensive glomerular capillary collapse, visceral epithelial cell hypertrophy and hyperplasia, and variable degree of tubulointerstitial inflammation. Such findings closely resemble those of HIV associated nephropathy(HIVAN) except endothelial inclusion body in HIVAN. Here we present, for the first time in Korea, a 16 yrs-old female patient with ESRD in a normal sized kidney. Nephrotic syndrome and hypertension were also accompanied. Serologically, she had no evidence of HIV infection. Though her symptom duration was somewhat shorter than that previously reported, her renal biopsy findings were those of collapsing glomerulopathy as previously described. Her renal function did not return to normal, and now she is on regular hemodialysis, waiting for renal transplantation.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Proteinuria
/
Biopsy
/
Capillaries
/
HIV Infections
/
Inclusion Bodies
/
Renal Dialysis
/
HIV
/
Kidney Transplantation
/
Epithelial Cells
/
Renal Insufficiency
Limits:
Female
/
Humans
Country/Region as subject:
Asia
Language:
Ko
Journal:
Korean Journal of Nephrology
Year:
2001
Type:
Article