Two Cases of Juvenile Granulosa Cell Tumor / 대한소아혈액종양학회지
Korean Journal of Pediatric Hematology-Oncology
;
: 146-152, 2000.
Article
in Korean
| WPRIM
| ID: wpr-99974
ABSTRACT
Juvenile granulosa cell tumor (JGCT) is one of the rare sex cord stromal tumors of the ovary. The majority of JGCT are found in prepubertal girls and young women. Unlike adult granulosa cell tumor (AGCT), JGCT is characterized by high frequency of mitosis and early relapse after treatment. Patients with JGCT in FIGO stage Ia have an excellent outcome with an event-free survival of about 90% following surgical resection alone, while those in advanced stages have an unfavorable outcome. We report two cases of JGCT in stage Ic, who showed a quite different outcome. One was managed initially with surgical resection alone and died of subsequent relapse. Another was managed with multimodality treatments including surgical resection, adjuvant chemotherapy and radiotherapy, and didn't show any evidence of relapse during 16 months of follow-up period. Further studies to evaluate the beneficial effects of chemotherapy and/or radiotherapy are required in patients with JGCT in stage Ic.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ovary
/
Radiotherapy
/
Recurrence
/
Follow-Up Studies
/
Chemotherapy, Adjuvant
/
Sex Cord-Gonadal Stromal Tumors
/
Disease-Free Survival
/
Drug Therapy
/
Granulosa Cell Tumor
/
Granulosa Cells
Type of study:
Observational study
/
Prognostic study
Limits:
Adult
/
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Pediatric Hematology-Oncology
Year:
2000
Type:
Article
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