A Case of Vitiligo Developed on the Sites of DNCB Application in a Patient with Alopecia Areata / 대한피부과학회지
Korean Journal of Dermatology
;
: 452-455, 2004.
Article
in Korean
| WPRIM
| ID: wpr-99987
ABSTRACT
We report a case of vitiligo developed on the sites of DNCB application for the treatment of alopecia areata in a 53-year-old woman. Histopathologic studies of the depigmented patches showed absence of melanin pigmentation at the basal layer of the epidermis and a negative reaction for the Fontana-Masson stain. The current theories explaining vitiligo development after topical sensitizer application are that topical sensitizers induce the vitiligo by a direct cytotoxic effect on the melanocytes, or by unmasking latent vitiligo as a result of the Koebner phenomenon due to contact dermatitis, but the exact mechanism is still unclear.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Vitiligo
/
Pigmentation
/
Dermatitis, Contact
/
Dinitrochlorobenzene
/
Epidermis
/
Alopecia
/
Alopecia Areata
/
Melanins
/
Melanocytes
Limits:
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2004
Type:
Article
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