Prescripción de fármacos bloqueadores del sistema renina angiotensina en pacientes con enfermedad renal crónica etapa 3 en atención primaria de salud / Prescription of renin-angiotensin-aldosterone system blockers in patients with stage 3 chronic kidney disease
Rev. méd. Chile
;
147(2): 173-180, Feb. 2019. tab, graf
Artículo
en Español
| LILACS
| ID: biblio-1004330
ABSTRACT
Background:
To reduce the progression of chronic kidney disease (CKD) and cardiovascular risk, the guidelines recommend the blockade of the renin-angiotensin-aldosterone system (RAAS) in patients with proteinuria.Aim:
To assess the frequency of enalapril or losartan use in diabetics or hypertensive patients with stage 3 CKD. Material andMethods:
Review of clinical records of patients with CKD in an urban primary care clinic.Results:
We identified 408 subjects aged 40 to 98 years (66% women) with stage 3 CKD. Sixty six percent had only hypertension and 34% were diabetic with or without hypertension. Seventy four percent received RAAS blockers (52% used enalapril, 45% losartan and 2% both medications). RAAS blockers were used in 70% of hypertensive and 78% of diabetic patients. The prescription in hypertensive diabetics with microalbuminuria was lower than in those without microalbuminuria (72% vs 87%, p < 0.05), but the opposite occurred in pure hypertensive patients with and without microalbuminuria (88% vs 69%, p < 0.05). There were no significant differences in blood pressure levels, microalbuminuria or serum potassium levels between RAAS blocker users and non-users. No differences were observed either between enalapril and losartan users.Conclusions:
The adherence to clinical guidelines is insufficient and users of the recommended drugs did not achieve the expected goals.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Inhibidores de la Enzima Convertidora de Angiotensina
/
Enalapril
/
Losartán
/
Insuficiencia Renal Crónica
Tipo de estudio:
Guía de Práctica Clínica
/
Estudio pronóstico
Límite:
Adulto
/
Anciano
/
Aged80
/
Femenino
/
Humanos
/
Masculino
Idioma:
Español
Revista:
Rev. méd. Chile
Asunto de la revista:
Medicina
Año:
2019
Tipo del documento:
Artículo
País de afiliación:
Chile
Institución/País de afiliación:
Universidad Austral de Chile/CL
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