Telomere length and childhood trauma in Colombians with depressive symptoms
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
;
41(3): 194-198, May-June 2019. tab
Artículo
en Inglés
| LILACS
| ID: biblio-1011493
ABSTRACT
Objective:
Childhood trauma and telomere length (TL) are important risk factors for major depressive disorder. We examined whether there was an association between childhood trauma and TL in a sample of Colombians who were assessed for depressive symptoms.Methods:
We applied the Center for Epidemiologic Studies Depression scale, the Patient Health Questionnaire-9, the Hospital Anxiety and Depression scale and the Childhood Trauma Questionnaire to 92 Colombian subjects (mean age = 21). TL was measured with quantitative PCR. Spearman's correlation coefficient (rs) was used to analyze the relationship between childhood trauma scores and TL.Results:
We found a significant correlation between TL and sexual abuse scores (rs = 0.428, p = 0.002) in individuals with higher depressive symptom scores.Conclusion:
This is the first report of a significant association between TL and sexual abuse in a Latin American sample and provides additional evidence about the role of childhood trauma and TL in neuropsychiatric disorders.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Maltrato a los Niños
/
Telómero
/
Trastorno Depresivo Mayor
/
Acortamiento del Telómero
Tipo de estudio:
Estudio diagnóstico
/
Investigación cualitativa
/
Factores de riesgo
Límite:
Niño
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America del Sur
/
Colombia
Idioma:
Inglés
Revista:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Asunto de la revista:
Psiquiatria
Año:
2019
Tipo del documento:
Artículo
País de afiliación:
Colombia
/
España
Institución/País de afiliación:
Universidad Antonio Nariño/CO
/
University of Barcelona/ES
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